All five men took themselves to two separate hospitals with life-threatening injuries.
“One of the men underwent treatment, however, died a short time later,” NSW Police said.
He is yet to be formally identified.
The other man remained in hospital in a stable condition.
About 10 minutes later, two men presented to Fairfield Hospital in a critical condition and were being treated, police said.
More than an hour later, at 9.50pm, the fifth man, believed to be a 19-year-old, appeared at Liverpool Hospital in a stable condition and was being treated for injuries.
Police set up a crime scene at a home in Canley Heights.
Officers attached to Fairfield City Police Area Command – with assistance from the State Crime Command’s Homicide Squad – are investigating.
Anyone with information can contact Crime Stoppers on 1800 333 000.
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